Cthrc1 gene
WebJan 29, 2013 · Colorectal cancer (CRC) patients with peritoneal carcinomatosis (PC) have a poor prognosis. Over the last decade, increasing evidence has suggested that the Collagen Triple Helix Repeat Containing 1 (CTHRC1) gene is involved in cancer progression and invasion. In this study, we investigated the expression of CTHRC1 in CRC and its … WebApr 17, 2024 · Collagen triple helix repeat containing-1 (CTHRC1) has been identified as cancer-related protein. ... The Structural Features of CTHRC1. The CTHRC1 gene is located at chromosome 8q22.3, and it contains …
Cthrc1 gene
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WebFeb 8, 2024 · We assessed the cause of elevated CTHRC1 levels. DNA methylation, gene mutation, CNV was critically involved in genetic and epigenetic regulation and were … WebAug 1, 2013 · Regulation of Cthrc1 gene expression by contact with hydroxyapatite and calcium. In order to gain further insight into the mechanism of Cthrc1 gene expression in osteoclasts, mature osteoclasts generated from BMMs ex vivo with M-CSF and RANKL were placed on different substrates, including a plastic dish, a dentin slice, or a …
WebWe recently identified collagen triple helix repeat containing-1 (Cthrc1) as a novel gene induced in adventitial fibroblasts after arterial injury. Cthrc1 is a 30 kDa secreted protein that has the ability to inhibit collagen matrix synthesis. Cthrc1 is also glycosylated and retains a signal sequence consistent with the presence of Cthrc1 in the ... http://www.informatics.jax.org/marker/MGI:1915838
WebDec 22, 2024 · The X-axis represent ligand and receptor pairs, with the first gene expressed on F13-Act-CTHRC1 cells and second gene expressed on the interacting cell types denoted in the Y-axis. Red: upregulated gene in tumor bulk RNA-seq. Blue: downregulated in tumor bulk (none present). WebJul 19, 2024 · Collagen triple helix repeat containing-1 (CTHRC1), highly expressed in multiple human solid tumors, has been identified as a tumor associated protein. …
WebCTHRC1. PROTEIN SUMMARY SECTION OVERVIEW RNA DATA ANTIBODY DATA. CTHRC1 INFORMATION. Proteini. Full gene name according to HGNC. Collagen triple …
WebMar 1, 2024 · Expression of CTHRC1 in Patients With COAD Under Different Physiological or Pathological States. UALCAN analysis showed that the expression level of CTHRC1 was significantly higher in the patients with primary COAD than that in normal tissues ().Notably, this abnormally high expression pattern is generally applicable to patients with different … earl wolfe nflWebMethods: DEGs were screened from four GEO (Gene Expression Omnibus) gene expression profiles. Gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses were performed. ... Collagen Type X Alpha 1 Chain (COL10A1), Collagen Triple Helix Repeat Containing 1 (CTHRC1), and Fibroblast Activation Protein (FAP) … csss seminarWebJul 29, 2013 · Collagen triple helix repeat containing-1 (CTHRC1) is a secreted glycoprotein that activates the planar cell polarity pathway of Wnt signaling. Using microarray analysis, we found that the CTHRC1 gene is overexpressed in hepatocellular carcinoma (HCC). The level of CTHRC1 mRNA was measured in 201 surgically resected … csss sfuWebCollagen triple helix repeat containing 1 is a protein that in humans is encoded by the CTHRC1 gene. Function. This locus encodes a protein that may play a role in the … css ssmWebGenomic Mutations. 2 involving Cthrc1. Incidental Mutations. Mutagenetix , APF. Find Mice (IMSR) 20 strains or lines available. Comparison Matrix. Gene Expression + Phenotype. … earl w. johnston roofing - hollywoodWebBackground: We discovered the gene Collagen Triple Helix Repeat Containing 1 (Cthrc1) and reported its developmental expression and induction in adventitial cells of injured … csss rouyn-norandaWebSep 21, 2011 · Orloff et al. (2011) identified a germline 131A-C transversion in exon 1 of the CTHRC1 gene, resulting in a gln44-to-pro (Q44P) substitution, in 1 (1.1%) of 116 patients of European descent with Barrett esophagus and/or esophageal adenocarcinoma ().The mutation was not found in 125 controls. The same mutation was found in 1 (1.7%) of 58 … earlwood animal hospital earlwood nsw