Cst phosphorylation
WebCertain proteins known to contain phosphorylated serine and threonine may not be detected by this antibody due to steric hindrance. The immunogen used is Phosphoserine and phosphothreonine conjugated with R-PE. The Life Science industry has been in the grips of a reproducibility crisis for a number of years. WebNov 9, 2024 · The anti-apoptotic myeloid cell leukemia 1 (MCL1) protein belongs to the pro-survival BCL2 family and is frequently amplified or elevated in human cancers. MCL1 is highly unstable, with its stability being regulated by phosphorylation and ubiquitination. Here, we identify acetylation as another crit …
Cst phosphorylation
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WebApr 13, 2024 · IntroductionObscurin (720–870 kDa) is a giant cytoskeletal and signaling protein that possesses both structural and regulatory functions in striated muscles. Immunoglobulin domains 58/59 (Ig58/59) of obscurin bind to a diverse set of proteins that are essential for the proper structure and function of the heart, including giant titin, novex … WebWestern Blotting Analysis: A 1:500 dilution of this antibody detected an increased SMAD1/5/8 phosphorylation in 10 µg lysate from BMP2-treated HEK293 cells. Target bands detection was blocked by the immunogen phosphopeptide, but not the corresponding non-phosphopeptide. Target description
WebJul 3, 2024 · Therefore, telomere length homeostasis is a balance between telomerase-extendable and CST-unextendable states. In our earlier work, we showed that Cdk1 also … WebCFTR functions as an ATP-gated, phosphorylation-regulated Cl- channel that mediates agonist … The cystic fibrosis transmembrane conductance regulator (CFTR) is the gene …
WebHTScan ® PDGF Receptor α Kinase Assay Kit. Figure 1. Time course of PDGFR-alpha kinase activity: DELFIA ® data generated using Phospho-Tyrosine mAbP-Tyr-100 #9411 to detect phosphorylation of PDGFR-alpha substrate peptide (#1305) by PDGFR-alpha kinase. In a 50 ul reaction, 10 Units PDGFR alpha and 1.5 uM substrate peptide were … WebCST is in a unique position to make seminal contributions to the field of protein modification proteomics: CST scientists have been at the forefront of the technological revolution in phosphoproteomics in recent years.
WebThe results showed that Met phosphorylation activated AMPK to inhibit mTOR phosphorylation and upregulated DOX-inhibited autophagy. Low expression of P62 also implied that the activation of AMPK was able to unblock autophagic flux and achieve protection against DOX-induced programmed cell death in cardiomyocytes ( Figs. 8 B, 8 …
WebJul 2, 2024 · We used antibodies against GSK-3α [Cell Signaling Technology (CST), #9338], GSK-3β (CST, #9315), phospho-GSK-3α (S21) (CST, #9316), phospho-GSK-3β (S9) (CST, #9336), β-catenin (CST, #9582), MCL-1 (Rockland, #600-401-394), p62 (Abcam, #ab91526), LC3 (MBL, #M186-3), phospho-H2AX (S139) (CST, #9718), H2AX (CST, … fine tooth hole saw bitserror in surv : time variable is not numericWebThis antibody recognises the phosphorylated serine found in the amino acid 2 position of the C-terminal domain repeat YSPTSPS. Tested applications Suitable for: ELISA, WB, IHC-P, ICC/IF more details Species reactivity Reacts with: … fine tooth metal fileWebDanvers, MA, October 31, 2007 – Cell Signaling Technology, Inc. (CST) announced today that it will make PhosphoScan ® Profiling, CST’s proprietary technology based on … fine tooth herb grinderWebPhospho-flow allows for the analysis of many phosphorylation events, along with cell surface markers, simultaneously. These types of experiments enable the experimenter to resolve complex biochemical signaling networks in heterogeneous cell populations. fine tooth or fine toothedWebThe phosphorylation of c-Myc has been investigated and previous studies have suggested a functional association between phosphorylation at Thr58/Ser62 by glycogen synthase kinase 3, cyclin dependent kinase, … error in system command cmd intern trueWebApr 4, 2024 · Further in-depth studies verified that PRKCI can interact with RIPK2 to promote PC growth and liver metastasis through enhancing phosphorylation of JNK, ERK and NF-κB signaling pathways. The broad phosphorylation activity of PRKCI and RIPK2 in PC pathogenesis provides candidate targets for effective intervention. fine tooth hand saw toolstation