Adiponectin-cre是什么
Web该Cre小鼠与FloxP小鼠交配后,在Cre特异表达的组织或者器官或细胞中,两个FloxP位点间的外显子或元件将被删除,达到条件性敲除或过表达的目的。 Cre-loxP重组系统是一种位点特异的基因重组技术,被广泛应用于特异位点的基因敲除、基因插入、基因翻转和基因 ... WebFeb 14, 2013 · To circumvent the possible side effects of gene deletion of the aP2-Cre in tissues other than adipocytes, two laboratories have developed adiponectin-Cre transgenic mice (Adipoq-Cre), with expression of a Cre recombinase driven by the promoter/regulatory regions of the mouse adiponectin locus using a bacterial artificial chromosome (BAC ...
Adiponectin-cre是什么
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WebThe Tg(Adipoq-cre)1Evdr mouse has become an important tool in adipose tissue biology. However, the exact genomic transgene integration site has not been established. Using … WebDec 3, 2024 · 脂联素(adiponectin,AdipoQ)是一种主要由脂肪组织分泌的脂肪细胞因子。近年来的研究表明,脂联素在调节动物脂质代谢中发挥重要的作用。
WebMay 3, 2016 · Adiponectin is a circulating hormone that is secreted almost exclusively by adipocytes. 23, 24 In the plasma, adiponectin exists as a full-length form and a globular … WebThe Jackson Laboratory adiponectin cre adipoq cre transgenic mice Adiponectin Cre Adipoq Cre Transgenic Mice, supplied by The Jackson Laboratory, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
WebThe promoter for adiponectin, a hormone secreted by mature adipocytes, has been used by multiple groups to generate adipocyte-specific Cre lines. 20, 21 The most widely used Adiponectin-Cre R line 12 has been shown several times to be specific to adipocytes, 9, 16, 18 and useful for targeting mature adipocytes in vivo.
WebMar 21, 2024 · ADIPOQ (Adiponectin, C1Q And Collagen Domain Containing) is a Protein Coding gene. Diseases associated with ADIPOQ include Adiponectin, Serum Level Of, Quantitative Trait Locus 1 and Fatty Liver Disease.Among its related pathways are AMP-activated protein kinase signaling and Integration of energy metabolism.Gene Ontology …
WebThe Tg(Adipoq-cre)1Evdr mouse has become an important tool in adipose tissue biology. However, the exact genomic transgene integration site has not been established. ... Characterization of the adiponectin promoter + Cre recombinase insertion in the Tg(Adipoq-cre)1Evdr mouse by targeted locus amplification and droplet digital PCR … mercure chantilly avisWebSep 29, 2024 · Adiponectin is a molecule secreted mainly by the body’s fat cells (adipocytes) that is linked to weight loss and weight gain. In this article, discover … mercure chantilly bookingWebJan 5, 2016 · We found that in both adiponectin-Cre ERT2; RFP and aP2-Cre ERT2; RFP mouse models, unilocular white adipocytes did not express UCP1 (Supplementary Fig. 3a,b). The various amounts of adipocyte-driver-labelled (30–40%) and -unlabelled (60–70%) beige adipocytes, which do express adiponectin and aP2 (ref. 8), present after cold … mercure chamonix tripadvisorWebAdiponectin (also referred to as GBP-28, apM1, AdipoQ and Acrp30) is a protein hormone and adipokine, which is involved in regulating glucose levels as well as fatty acid … mercure chantilly restaurantWebMar 16, 2024 · Adiponectin-expressing EGFP + cells collected from the thymus of 5-week-old Adn-Cre/ROSA mT/mG mice were adoptively transferred (30000 EGFP + cells/mouse by tail vein injection) into sub-lethally ... mercure chamonix centre bookingWebJun 24, 2024 · Cre- littermates serve as control. In keeping with the unique expression of adiponectin Cre in adipocytes and their precursors all Cre+ products of the mating contain no discernable WAT confirmed by virtually undetectable circulating adiponectin or leptin as well as visfatin and, resistin . BAT is also absent and as a result, FF mice are cold ... mercure charlestown restaurantWebThe Cre-lox system, derived from P1 bacteriophage, is a potent and specific system for controlling gene expression. The protein Cre recombinase recognizes 34 bp loxP sites, and the orientation and location of the loxP sites determines how the genetic material will be rearranged. The schematic below shows the three types of rearrangements ... mercure chantilly resort